Invasive meningococcal disease in Malta: an epidemiological overview, 1994–2007

Immunological Aspect of Meningococcal disease: An overview in Host- Bacteria Interaction

Meningococcal disease remains a significant global public health and is unique among causes of bacterial meningitis and sepsis where it not only causes sporadic disease but also outbreaks. Meningococcal disease has a rapid onset with high mortality. The understanding of immunopathogenesis is crucial for development of novel therapeutic strategies and vaccines designed against meningococcal dise...

Invasive meningococcal disease in childhood.

Evolution towards criticality in an epidemiological model for meningococcal disease

In a model for bacterial infections with various mutants we find the epidemiological system evolving towards criticality without outer tuning of a control parameter. This is an indication for self-organized criticality. The epidemic model is a susceptible–infected–recovered hosts system (SIR) for the harmless agent infecting hosts I , acting as a background to a mutant strain Y which occasional...

Need for Optimisation of Immunisation Strategies Targeting Invasive Meningococcal Disease in the Netherlands

Invasive meningococcal disease (IMD) is a severe bacterial infectious disease with high mortality and morbidity rates worldwide. In recent years, industrialised countries have implemented vaccines targeting IMD in their National Immunisation Programmes (NIPs). In 2002, the Netherlands successfully implemented a single dose of meningococcal serogroup C conjugate vaccine at the age of 14 months a...

An Overview of Immunogenetic in Celiac Disease

Introduction: Celiac disease is an autoimmune disease caused by persistent intolerance to gluten, which is causedin people who are genetically predisposed. The disease presents with atrophy of the small intestinal mucosa and gastrointestinal and extra-gastrointestinal manifestations.Environmental factors like gluten and genetic factors such as HLA and non-HLA genes are involved in causing the d...